Our group develops novel statistical and computational methods to
address important problems in biology and medicine. We collaborate
with research groups at Yale and other institutions to apply our
methods to study the biological basis and treatment strategies for
many diseases, including lung diseases, cancer, substance dependence,
psychiatric disorders (major depression, schizophrenia, bipolar,
post-traumatic stress disorder), cardiovascular diseases, autism,
congenital heart diseases, aneurysm, hypertension, and others.
We also collaborate with plant geneticists and evolutionary
biologists using next generation sequencing and microarrays
to identify genetic associations with various traits.